GrippeFranceV1, Main, Exploration, bibRecord, 000017

The dynamics and interactions of respiratory pathogen carriage among French pilgrims during the 2018 Hajj.

Identifieur interne : 000017 ( Main/Exploration ); précédent : 000016; suivant : 000018

The dynamics and interactions of respiratory pathogen carriage among French pilgrims during the 2018 Hajj.

Auteurs : Van-Thuan Hoang [France, Viêt Nam] ; Thi-Loi Dao [France, Viêt Nam] ; Tran Duc Anh Ly [France] ; Khadidja Belhouchat [France] ; Kamel Larbi Chaht [France] ; Jean Gaudart [France] ; Bakridine Mmadi Mrenda [France] ; Tassadit Drali [France] ; Saber Yezli [Arabie saoudite] ; Badriah Alotaibi [Arabie saoudite] ; Pierre-Edouard Fournier [France] ; Didier Raoult [France] ; Philippe Parola [France] ; Vincent Pommier De Santi [France] ; Philippe Gautret [France]

Source :

Emerging microbes & infections [ 2222-1751 ] ; 2019.

RBID : pubmed:31749410

Descripteurs français

KwdFr :
- Adulte (MeSH), Adulte d'âge moyen (MeSH), Arabie saoudite (MeSH), Bactéries (classification), Bactéries (génétique), Bactéries (isolement et purification), Femelle (MeSH), France (MeSH), Humains (MeSH), Infections bactériennes (microbiologie), Infections de l'appareil respiratoire (microbiologie), Infections de l'appareil respiratoire (virologie), Maladies virales (virologie), Mâle (MeSH), Sujet âgé (MeSH), Sujet âgé de 80 ans ou plus (MeSH), Virus (classification), Virus (génétique), Virus (isolement et purification), Voyage (MeSH).
MESH :
- génétique : Bactéries, Virus.
- isolement et purification : Bactéries, Virus.
- microbiologie : Infections bactériennes, Infections de l'appareil respiratoire.
- virologie : Infections de l'appareil respiratoire, Maladies virales.
- Adulte, Adulte d'âge moyen, Arabie saoudite, Bactéries, Femelle, France, Humains, Mâle, Sujet âgé, Sujet âgé de 80 ans ou plus, Virus, Voyage.
Wicri :
- geographic : France, Arabie saoudite.

English descriptors

KwdEn :
- Adult (MeSH), Aged (MeSH), Aged, 80 and over (MeSH), Bacteria (classification), Bacteria (genetics), Bacteria (isolation & purification), Bacterial Infections (microbiology), Female (MeSH), France (MeSH), Humans (MeSH), Male (MeSH), Middle Aged (MeSH), Respiratory Tract Infections (microbiology), Respiratory Tract Infections (virology), Saudi Arabia (MeSH), Travel (MeSH), Virus Diseases (virology), Viruses (classification), Viruses (genetics), Viruses (isolation & purification).
MESH :
- geographic : France, Saudi Arabia.
- classification : Bacteria, Viruses.
- genetics : Bacteria, Viruses.
- isolation & purification : Bacteria, Viruses.
- microbiology : Bacterial Infections, Respiratory Tract Infections.
- virology : Respiratory Tract Infections, Virus Diseases.
- Adult, Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Travel.

Abstract

We conducted this study to describe the dynamics of the acquisition of respiratory pathogens, their potential interactions and risk factors for possible lower respiratory tract infection symptoms (LRTI) among French pilgrims during the 2018 Hajj. Each participant underwent four successive systematic nasopharyngeal swabs before and during their stay in Saudi Arabia. Carriage of the main respiratory pathogens was assessed by PCR. 121 pilgrims were included and 93.4% reported respiratory symptoms during the study period. The acquisition of rhinovirus, coronaviruses and Staphylococcus aureus occurred soon after arrival in Saudi Arabia and rates decreased gradually after days 5 and 6. In contrast, Streptococcus pneumoniae and Klebsiella pneumoniae carriage increased progressively until the end of the stay in Saudi Arabia. Haemophilus influenzae and Moraxella catarrhalis carriage increased starting around days 12 and 13, following an initial clearance. Influenza viruses were rarely isolated. We observed an independent positive mutual association between S. aureus and rhinovirus carriage and between H. influenzae and M. catarrhalis carriage. Dual carriage of H. influenzae and M. catarrhalis was strongly associated with S. pneumoniae carriage (OR = 6.22). Finally, our model showed that M. catarrhalis carriage was negatively associated with K. pneumoniae carriage. Chronic respiratory disease was associated with symptoms of LRTI. K. pneumoniae, M. catarrhalis-S. aureus and H. influenzae-rhinovirus dual carriage was associated with LRTI symptoms. Our data suggest that RTIs at the Hajj are a result of complex interactions between a number of respiratory viruses and bacteria.

DOI: 10.1080/22221751.2019.1693247
PubMed: 31749410
PubMed Central: PMC6882464

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000009
to stream Main, to step Curation: 000009

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The dynamics and interactions of respiratory pathogen carriage among French pilgrims during the 2018 Hajj.</title>
<author><name sortKey="Hoang, Van Thuan" sort="Hoang, Van Thuan" uniqKey="Hoang V" first="Van-Thuan" last="Hoang">Van-Thuan Hoang</name>
<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>IHU-Méditerranée Infection, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IHU-Méditerranée Infection, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>Thai Binh University of Medicine and Pharmacy, Thai Binh, Viet Nam.</nlm:affiliation>
<country xml:lang="fr">Viêt Nam</country>
<wicri:regionArea>Thai Binh University of Medicine and Pharmacy, Thai Binh</wicri:regionArea>
<wicri:noRegion>Thai Binh</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Dao, Thi Loi" sort="Dao, Thi Loi" uniqKey="Dao T" first="Thi-Loi" last="Dao">Thi-Loi Dao</name>
<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>IHU-Méditerranée Infection, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IHU-Méditerranée Infection, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>Thai Binh University of Medicine and Pharmacy, Thai Binh, Viet Nam.</nlm:affiliation>
<country xml:lang="fr">Viêt Nam</country>
<wicri:regionArea>Thai Binh University of Medicine and Pharmacy, Thai Binh</wicri:regionArea>
<wicri:noRegion>Thai Binh</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ly, Tran Duc Anh" sort="Ly, Tran Duc Anh" uniqKey="Ly T" first="Tran Duc Anh" last="Ly">Tran Duc Anh Ly</name>
<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>IHU-Méditerranée Infection, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IHU-Méditerranée Infection, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Belhouchat, Khadidja" sort="Belhouchat, Khadidja" uniqKey="Belhouchat K" first="Khadidja" last="Belhouchat">Khadidja Belhouchat</name>
<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>IHU-Méditerranée Infection, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IHU-Méditerranée Infection, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Chaht, Kamel Larbi" sort="Chaht, Kamel Larbi" uniqKey="Chaht K" first="Kamel Larbi" last="Chaht">Kamel Larbi Chaht</name>
<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>IHU-Méditerranée Infection, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IHU-Méditerranée Infection, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gaudart, Jean" sort="Gaudart, Jean" uniqKey="Gaudart J" first="Jean" last="Gaudart">Jean Gaudart</name>
<affiliation wicri:level="1"><nlm:affiliation>Aix Marseille Univ, INSERM, IRD, SESSTIM UMR1252, Faculty of Medicine Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, INSERM, IRD, SESSTIM UMR1252, Faculty of Medicine Marseille</wicri:regionArea>
<wicri:noRegion>Faculty of Medicine Marseille</wicri:noRegion>
<wicri:noRegion>Faculty of Medicine Marseille</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>APHM, La Timone Hospital, Biostatistics & ICT Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>APHM, La Timone Hospital, Biostatistics & ICT Marseille</wicri:regionArea>
<wicri:noRegion>Biostatistics & ICT Marseille</wicri:noRegion>
<wicri:noRegion>Biostatistics & ICT Marseille</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mrenda, Bakridine Mmadi" sort="Mrenda, Bakridine Mmadi" uniqKey="Mrenda B" first="Bakridine Mmadi" last="Mrenda">Bakridine Mmadi Mrenda</name>
<affiliation wicri:level="3"><nlm:affiliation>French Military Centre for Epidemiology and Public Health, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>French Military Centre for Epidemiology and Public Health, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Drali, Tassadit" sort="Drali, Tassadit" uniqKey="Drali T" first="Tassadit" last="Drali">Tassadit Drali</name>
<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>IHU-Méditerranée Infection, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IHU-Méditerranée Infection, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Yezli, Saber" sort="Yezli, Saber" uniqKey="Yezli S" first="Saber" last="Yezli">Saber Yezli</name>
<affiliation wicri:level="1"><nlm:affiliation>The Global Centre for Mass Gatherings Medicine, Ministry of Health, Riyadh, Saudi Arabia.</nlm:affiliation>
<country xml:lang="fr">Arabie saoudite</country>
<wicri:regionArea>The Global Centre for Mass Gatherings Medicine, Ministry of Health, Riyadh</wicri:regionArea>
<wicri:noRegion>Riyadh</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Alotaibi, Badriah" sort="Alotaibi, Badriah" uniqKey="Alotaibi B" first="Badriah" last="Alotaibi">Badriah Alotaibi</name>
<affiliation wicri:level="1"><nlm:affiliation>The Global Centre for Mass Gatherings Medicine, Ministry of Health, Riyadh, Saudi Arabia.</nlm:affiliation>
<country xml:lang="fr">Arabie saoudite</country>
<wicri:regionArea>The Global Centre for Mass Gatherings Medicine, Ministry of Health, Riyadh</wicri:regionArea>
<wicri:noRegion>Riyadh</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Fournier, Pierre Edouard" sort="Fournier, Pierre Edouard" uniqKey="Fournier P" first="Pierre-Edouard" last="Fournier">Pierre-Edouard Fournier</name>
<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>IHU-Méditerranée Infection, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IHU-Méditerranée Infection, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Raoult, Didier" sort="Raoult, Didier" uniqKey="Raoult D" first="Didier" last="Raoult">Didier Raoult</name>
<affiliation wicri:level="3"><nlm:affiliation>IHU-Méditerranée Infection, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IHU-Méditerranée Infection, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, AP-HM, MEPHI, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, IRD, AP-HM, MEPHI, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Parola, Philippe" sort="Parola, Philippe" uniqKey="Parola P" first="Philippe" last="Parola">Philippe Parola</name>
<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>IHU-Méditerranée Infection, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IHU-Méditerranée Infection, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="De Santi, Vincent Pommier" sort="De Santi, Vincent Pommier" uniqKey="De Santi V" first="Vincent Pommier" last="De Santi">Vincent Pommier De Santi</name>
<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>IHU-Méditerranée Infection, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IHU-Méditerranée Infection, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>French Military Centre for Epidemiology and Public Health, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>French Military Centre for Epidemiology and Public Health, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gautret, Philippe" sort="Gautret, Philippe" uniqKey="Gautret P" first="Philippe" last="Gautret">Philippe Gautret</name>
<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>IHU-Méditerranée Infection, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IHU-Méditerranée Infection, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2019">2019</date>
<idno type="RBID">pubmed:31749410</idno>
<idno type="pmid">31749410</idno>
<idno type="doi">10.1080/22221751.2019.1693247</idno>
<idno type="pmc">PMC6882464</idno>
<idno type="wicri:Area/Main/Corpus">000009</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000009</idno>
<idno type="wicri:Area/Main/Curation">000009</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000009</idno>
<idno type="wicri:Area/Main/Exploration">000009</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">The dynamics and interactions of respiratory pathogen carriage among French pilgrims during the 2018 Hajj.</title>
<author><name sortKey="Hoang, Van Thuan" sort="Hoang, Van Thuan" uniqKey="Hoang V" first="Van-Thuan" last="Hoang">Van-Thuan Hoang</name>
<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>IHU-Méditerranée Infection, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IHU-Méditerranée Infection, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>Thai Binh University of Medicine and Pharmacy, Thai Binh, Viet Nam.</nlm:affiliation>
<country xml:lang="fr">Viêt Nam</country>
<wicri:regionArea>Thai Binh University of Medicine and Pharmacy, Thai Binh</wicri:regionArea>
<wicri:noRegion>Thai Binh</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Dao, Thi Loi" sort="Dao, Thi Loi" uniqKey="Dao T" first="Thi-Loi" last="Dao">Thi-Loi Dao</name>
<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>IHU-Méditerranée Infection, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IHU-Méditerranée Infection, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>Thai Binh University of Medicine and Pharmacy, Thai Binh, Viet Nam.</nlm:affiliation>
<country xml:lang="fr">Viêt Nam</country>
<wicri:regionArea>Thai Binh University of Medicine and Pharmacy, Thai Binh</wicri:regionArea>
<wicri:noRegion>Thai Binh</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ly, Tran Duc Anh" sort="Ly, Tran Duc Anh" uniqKey="Ly T" first="Tran Duc Anh" last="Ly">Tran Duc Anh Ly</name>
<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>IHU-Méditerranée Infection, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IHU-Méditerranée Infection, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Belhouchat, Khadidja" sort="Belhouchat, Khadidja" uniqKey="Belhouchat K" first="Khadidja" last="Belhouchat">Khadidja Belhouchat</name>
<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>IHU-Méditerranée Infection, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IHU-Méditerranée Infection, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Chaht, Kamel Larbi" sort="Chaht, Kamel Larbi" uniqKey="Chaht K" first="Kamel Larbi" last="Chaht">Kamel Larbi Chaht</name>
<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>IHU-Méditerranée Infection, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IHU-Méditerranée Infection, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gaudart, Jean" sort="Gaudart, Jean" uniqKey="Gaudart J" first="Jean" last="Gaudart">Jean Gaudart</name>
<affiliation wicri:level="1"><nlm:affiliation>Aix Marseille Univ, INSERM, IRD, SESSTIM UMR1252, Faculty of Medicine Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, INSERM, IRD, SESSTIM UMR1252, Faculty of Medicine Marseille</wicri:regionArea>
<wicri:noRegion>Faculty of Medicine Marseille</wicri:noRegion>
<wicri:noRegion>Faculty of Medicine Marseille</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>APHM, La Timone Hospital, Biostatistics & ICT Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>APHM, La Timone Hospital, Biostatistics & ICT Marseille</wicri:regionArea>
<wicri:noRegion>Biostatistics & ICT Marseille</wicri:noRegion>
<wicri:noRegion>Biostatistics & ICT Marseille</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mrenda, Bakridine Mmadi" sort="Mrenda, Bakridine Mmadi" uniqKey="Mrenda B" first="Bakridine Mmadi" last="Mrenda">Bakridine Mmadi Mrenda</name>
<affiliation wicri:level="3"><nlm:affiliation>French Military Centre for Epidemiology and Public Health, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>French Military Centre for Epidemiology and Public Health, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Drali, Tassadit" sort="Drali, Tassadit" uniqKey="Drali T" first="Tassadit" last="Drali">Tassadit Drali</name>
<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>IHU-Méditerranée Infection, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IHU-Méditerranée Infection, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Yezli, Saber" sort="Yezli, Saber" uniqKey="Yezli S" first="Saber" last="Yezli">Saber Yezli</name>
<affiliation wicri:level="1"><nlm:affiliation>The Global Centre for Mass Gatherings Medicine, Ministry of Health, Riyadh, Saudi Arabia.</nlm:affiliation>
<country xml:lang="fr">Arabie saoudite</country>
<wicri:regionArea>The Global Centre for Mass Gatherings Medicine, Ministry of Health, Riyadh</wicri:regionArea>
<wicri:noRegion>Riyadh</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Alotaibi, Badriah" sort="Alotaibi, Badriah" uniqKey="Alotaibi B" first="Badriah" last="Alotaibi">Badriah Alotaibi</name>
<affiliation wicri:level="1"><nlm:affiliation>The Global Centre for Mass Gatherings Medicine, Ministry of Health, Riyadh, Saudi Arabia.</nlm:affiliation>
<country xml:lang="fr">Arabie saoudite</country>
<wicri:regionArea>The Global Centre for Mass Gatherings Medicine, Ministry of Health, Riyadh</wicri:regionArea>
<wicri:noRegion>Riyadh</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Fournier, Pierre Edouard" sort="Fournier, Pierre Edouard" uniqKey="Fournier P" first="Pierre-Edouard" last="Fournier">Pierre-Edouard Fournier</name>
<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>IHU-Méditerranée Infection, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IHU-Méditerranée Infection, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Raoult, Didier" sort="Raoult, Didier" uniqKey="Raoult D" first="Didier" last="Raoult">Didier Raoult</name>
<affiliation wicri:level="3"><nlm:affiliation>IHU-Méditerranée Infection, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IHU-Méditerranée Infection, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, AP-HM, MEPHI, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, IRD, AP-HM, MEPHI, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Parola, Philippe" sort="Parola, Philippe" uniqKey="Parola P" first="Philippe" last="Parola">Philippe Parola</name>
<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>IHU-Méditerranée Infection, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IHU-Méditerranée Infection, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="De Santi, Vincent Pommier" sort="De Santi, Vincent Pommier" uniqKey="De Santi V" first="Vincent Pommier" last="De Santi">Vincent Pommier De Santi</name>
<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>IHU-Méditerranée Infection, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IHU-Méditerranée Infection, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>French Military Centre for Epidemiology and Public Health, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>French Military Centre for Epidemiology and Public Health, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gautret, Philippe" sort="Gautret, Philippe" uniqKey="Gautret P" first="Philippe" last="Gautret">Philippe Gautret</name>
<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>IHU-Méditerranée Infection, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>IHU-Méditerranée Infection, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">Emerging microbes & infections</title>
<idno type="eISSN">2222-1751</idno>
<imprint><date when="2019" type="published">2019</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult (MeSH)</term>
<term>Aged (MeSH)</term>
<term>Aged, 80 and over (MeSH)</term>
<term>Bacteria (classification)</term>
<term>Bacteria (genetics)</term>
<term>Bacteria (isolation & purification)</term>
<term>Bacterial Infections (microbiology)</term>
<term>Female (MeSH)</term>
<term>France (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Male (MeSH)</term>
<term>Middle Aged (MeSH)</term>
<term>Respiratory Tract Infections (microbiology)</term>
<term>Respiratory Tract Infections (virology)</term>
<term>Saudi Arabia (MeSH)</term>
<term>Travel (MeSH)</term>
<term>Virus Diseases (virology)</term>
<term>Viruses (classification)</term>
<term>Viruses (genetics)</term>
<term>Viruses (isolation & purification)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte (MeSH)</term>
<term>Adulte d'âge moyen (MeSH)</term>
<term>Arabie saoudite (MeSH)</term>
<term>Bactéries (classification)</term>
<term>Bactéries (génétique)</term>
<term>Bactéries (isolement et purification)</term>
<term>Femelle (MeSH)</term>
<term>France (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Infections bactériennes (microbiologie)</term>
<term>Infections de l'appareil respiratoire (microbiologie)</term>
<term>Infections de l'appareil respiratoire (virologie)</term>
<term>Maladies virales (virologie)</term>
<term>Mâle (MeSH)</term>
<term>Sujet âgé (MeSH)</term>
<term>Sujet âgé de 80 ans ou plus (MeSH)</term>
<term>Virus (classification)</term>
<term>Virus (génétique)</term>
<term>Virus (isolement et purification)</term>
<term>Voyage (MeSH)</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>France</term>
<term>Saudi Arabia</term>
</keywords>
<keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Bacteria</term>
<term>Viruses</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Bacteria</term>
<term>Viruses</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Bactéries</term>
<term>Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Bacteria</term>
<term>Viruses</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Bactéries</term>
<term>Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiologie" xml:lang="fr"><term>Infections bactériennes</term>
<term>Infections de l'appareil respiratoire</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Bacterial Infections</term>
<term>Respiratory Tract Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections de l'appareil respiratoire</term>
<term>Maladies virales</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Respiratory Tract Infections</term>
<term>Virus Diseases</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Travel</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Arabie saoudite</term>
<term>Bactéries</term>
<term>Femelle</term>
<term>France</term>
<term>Humains</term>
<term>Mâle</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Virus</term>
<term>Voyage</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>France</term>
<term>Arabie saoudite</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">We conducted this study to describe the dynamics of the acquisition of respiratory pathogens, their potential interactions and risk factors for possible lower respiratory tract infection symptoms (LRTI) among French pilgrims during the 2018 Hajj. Each participant underwent four successive systematic nasopharyngeal swabs before and during their stay in Saudi Arabia. Carriage of the main respiratory pathogens was assessed by PCR. 121 pilgrims were included and 93.4% reported respiratory symptoms during the study period. The acquisition of rhinovirus, coronaviruses and S<i>taphylococcus aureus</i>
 occurred soon after arrival in Saudi Arabia and rates decreased gradually after days 5 and 6. In contrast, <i>Streptococcus pneumoniae</i>
 and <i>Klebsiella pneumoniae</i>
 carriage increased progressively until the end of the stay in Saudi Arabia. <i>Haemophilus influenzae</i>
 and <i>Moraxella catarrhalis</i>
 carriage increased starting around days 12 and 13, following an initial clearance. Influenza viruses were rarely isolated. We observed an independent positive mutual association between <i>S. aureus</i>
 and rhinovirus carriage and between <i>H. influenzae</i>
 and <i>M. catarrhalis</i>
 carriage<i>.</i>
 Dual carriage of <i>H. influenzae</i>
 and <i>M. catarrhalis</i>
 was strongly associated with <i>S. pneumoniae</i>
 carriage (OR = 6.22). Finally, our model showed that <i>M. catarrhalis</i>
 carriage was negatively associated with <i>K. pneumoniae</i>
 carriage. Chronic respiratory disease was associated with symptoms of LRTI. <i>K. pneumoniae, M. catarrhalis-S. aureus</i>
 and <i>H. influenzae</i>
-rhinovirus dual carriage was associated with LRTI symptoms. Our data suggest that RTIs at the Hajj are a result of complex interactions between a number of respiratory viruses and bacteria.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">31749410</PMID>
<DateCompleted><Year>2019</Year>
<Month>12</Month>
<Day>09</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>01</Month>
<Day>08</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">2222-1751</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>8</Volume>
<Issue>1</Issue>
<PubDate><Year>2019</Year>
</PubDate>
</JournalIssue>
<Title>Emerging microbes & infections</Title>
<ISOAbbreviation>Emerg Microbes Infect</ISOAbbreviation>
</Journal>
<ArticleTitle>The dynamics and interactions of respiratory pathogen carriage among French pilgrims during the 2018 Hajj.</ArticleTitle>
<Pagination><MedlinePgn>1701-1710</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1080/22221751.2019.1693247</ELocationID>
<Abstract><AbstractText>We conducted this study to describe the dynamics of the acquisition of respiratory pathogens, their potential interactions and risk factors for possible lower respiratory tract infection symptoms (LRTI) among French pilgrims during the 2018 Hajj. Each participant underwent four successive systematic nasopharyngeal swabs before and during their stay in Saudi Arabia. Carriage of the main respiratory pathogens was assessed by PCR. 121 pilgrims were included and 93.4% reported respiratory symptoms during the study period. The acquisition of rhinovirus, coronaviruses and S<i>taphylococcus aureus</i>
 occurred soon after arrival in Saudi Arabia and rates decreased gradually after days 5 and 6. In contrast, <i>Streptococcus pneumoniae</i>
 and <i>Klebsiella pneumoniae</i>
 carriage increased progressively until the end of the stay in Saudi Arabia. <i>Haemophilus influenzae</i>
 and <i>Moraxella catarrhalis</i>
 carriage increased starting around days 12 and 13, following an initial clearance. Influenza viruses were rarely isolated. We observed an independent positive mutual association between <i>S. aureus</i>
 and rhinovirus carriage and between <i>H. influenzae</i>
 and <i>M. catarrhalis</i>
 carriage<i>.</i>
 Dual carriage of <i>H. influenzae</i>
 and <i>M. catarrhalis</i>
 was strongly associated with <i>S. pneumoniae</i>
 carriage (OR = 6.22). Finally, our model showed that <i>M. catarrhalis</i>
 carriage was negatively associated with <i>K. pneumoniae</i>
 carriage. Chronic respiratory disease was associated with symptoms of LRTI. <i>K. pneumoniae, M. catarrhalis-S. aureus</i>
 and <i>H. influenzae</i>
-rhinovirus dual carriage was associated with LRTI symptoms. Our data suggest that RTIs at the Hajj are a result of complex interactions between a number of respiratory viruses and bacteria.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Hoang</LastName>
<ForeName>Van-Thuan</ForeName>
<Initials>VT</Initials>
<AffiliationInfo><Affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>IHU-Méditerranée Infection, Marseille, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Thai Binh University of Medicine and Pharmacy, Thai Binh, Viet Nam.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Dao</LastName>
<ForeName>Thi-Loi</ForeName>
<Initials>TL</Initials>
<AffiliationInfo><Affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>IHU-Méditerranée Infection, Marseille, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Thai Binh University of Medicine and Pharmacy, Thai Binh, Viet Nam.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ly</LastName>
<ForeName>Tran Duc Anh</ForeName>
<Initials>TDA</Initials>
<AffiliationInfo><Affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>IHU-Méditerranée Infection, Marseille, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Belhouchat</LastName>
<ForeName>Khadidja</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>IHU-Méditerranée Infection, Marseille, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chaht</LastName>
<ForeName>Kamel Larbi</ForeName>
<Initials>KL</Initials>
<AffiliationInfo><Affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>IHU-Méditerranée Infection, Marseille, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gaudart</LastName>
<ForeName>Jean</ForeName>
<Initials>J</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0001-9006-5729</Identifier>
<AffiliationInfo><Affiliation>Aix Marseille Univ, INSERM, IRD, SESSTIM UMR1252, Faculty of Medicine Marseille, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>APHM, La Timone Hospital, Biostatistics & ICT Marseille, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mrenda</LastName>
<ForeName>Bakridine Mmadi</ForeName>
<Initials>BM</Initials>
<AffiliationInfo><Affiliation>French Military Centre for Epidemiology and Public Health, Marseille, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Drali</LastName>
<ForeName>Tassadit</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>IHU-Méditerranée Infection, Marseille, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Yezli</LastName>
<ForeName>Saber</ForeName>
<Initials>S</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0002-3380-7092</Identifier>
<AffiliationInfo><Affiliation>The Global Centre for Mass Gatherings Medicine, Ministry of Health, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Alotaibi</LastName>
<ForeName>Badriah</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>The Global Centre for Mass Gatherings Medicine, Ministry of Health, Riyadh, Saudi Arabia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fournier</LastName>
<ForeName>Pierre-Edouard</ForeName>
<Initials>PE</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0001-8463-8885</Identifier>
<AffiliationInfo><Affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>IHU-Méditerranée Infection, Marseille, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Raoult</LastName>
<ForeName>Didier</ForeName>
<Initials>D</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0002-0633-5974</Identifier>
<AffiliationInfo><Affiliation>IHU-Méditerranée Infection, Marseille, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Aix Marseille Univ, IRD, AP-HM, MEPHI, Marseille, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Parola</LastName>
<ForeName>Philippe</ForeName>
<Initials>P</Initials>
<Identifier Source="ORCID">https://orcid.org/0000-0002-1061-1927</Identifier>
<AffiliationInfo><Affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>IHU-Méditerranée Infection, Marseille, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>de Santi</LastName>
<ForeName>Vincent Pommier</ForeName>
<Initials>VP</Initials>
<AffiliationInfo><Affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>IHU-Méditerranée Infection, Marseille, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>French Military Centre for Epidemiology and Public Health, Marseille, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gautret</LastName>
<ForeName>Philippe</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>IHU-Méditerranée Infection, Marseille, France.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Emerg Microbes Infect</MedlineTA>
<NlmUniqueID>101594885</NlmUniqueID>
<ISSNLinking>2222-1751</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001419" MajorTopicYN="N">Bacteria</DescriptorName>
<QualifierName UI="Q000145" MajorTopicYN="N">classification</QualifierName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001424" MajorTopicYN="N">Bacterial Infections</DescriptorName>
<QualifierName UI="Q000382" MajorTopicYN="Y">microbiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005602" MajorTopicYN="N" Type="Geographic">France</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012141" MajorTopicYN="N">Respiratory Tract Infections</DescriptorName>
<QualifierName UI="Q000382" MajorTopicYN="Y">microbiology</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012529" MajorTopicYN="N" Type="Geographic">Saudi Arabia</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014195" MajorTopicYN="N">Travel</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014777" MajorTopicYN="N">Virus Diseases</DescriptorName>
<QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014780" MajorTopicYN="N">Viruses</DescriptorName>
<QualifierName UI="Q000145" MajorTopicYN="N">classification</QualifierName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Hajj</Keyword>
<Keyword MajorTopicYN="N">pathogen interaction</Keyword>
<Keyword MajorTopicYN="N">pilgrims</Keyword>
<Keyword MajorTopicYN="N">respiratory tract infections</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2019</Year>
<Month>11</Month>
<Day>22</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2019</Year>
<Month>11</Month>
<Day>22</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2019</Year>
<Month>12</Month>
<Day>18</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">31749410</ArticleId>
<ArticleId IdType="doi">10.1080/22221751.2019.1693247</ArticleId>
<ArticleId IdType="pmc">PMC6882464</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>Clin Infect Dis. 2013 Oct;57(7):992-1000</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23839997</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2011 Feb 09;6(2):e16142</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21347398</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Travel Med Infect Dis. 2017 Sep;19:2-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29037978</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2019 May 18;393(10185):2073-2084</Citation>
<ArticleIdList><ArticleId IdType="pubmed">31106753</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Travel Med Infect Dis. 2019 Sep - Oct;31:101343</Citation>
<ArticleIdList><ArticleId IdType="pubmed">30415081</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Pathog Dis. 2014 Apr;70(3):280-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24391058</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2018 Apr 12;13(4):e0195098</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29649269</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Int J Infect Dis. 2008 Jan;12(1):102-3</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17540601</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Travel Med Infect Dis. 2019 Jul - Aug;30:32-38</Citation>
<ArticleIdList><ArticleId IdType="pubmed">30858034</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2008 Oct;14(10):1584-91</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18826823</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vaccine. 2018 Nov 19;36(48):7415-7422</Citation>
<ArticleIdList><ArticleId IdType="pubmed">30236632</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect Dis. 2011 Feb 15;203(4):549-55</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21220774</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Microbiol Infect. 2015 Jun;21(6):571.e1-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25700892</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2014 Nov;20(11):1821-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25341199</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Travel Med Infect Dis. 2014 Sep-Oct;12(5):429-42</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24999278</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2003 Jun 28;361(9376):2189-95</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12842372</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Infect Control Hosp Epidemiol. 2004 Jun;25(6):504-11</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15242200</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Theor Biol. 2008 Sep 21;254(2):499-507</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18606170</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Infect Dis Rep. 2018 Aug 28;20(11):44</Citation>
<ArticleIdList><ArticleId IdType="pubmed">30155747</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect. 2013 Mar;66(3):247-54</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23266462</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Microbiol Infect. 2015 Jan;21(1):77.e11-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25636939</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Front Immunol. 2018 Nov 16;9:2640</Citation>
<ArticleIdList><ArticleId IdType="pubmed">30505304</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2012;7(10):e47711</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23082199</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Rev Microbiol. 2010 May;8(5):340-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20348933</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Microbiol. 2003 Apr;41(4):1386-90</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12682118</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect Public Health. 2018 Mar - Apr;11(2):165-170</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28668659</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>BMC Infect Dis. 2015 Aug 14;15:336</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26271750</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Infect Control Hosp Epidemiol. 2005 Feb;26(2):196-203</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15756892</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2012 Nov;18(11):1738-45</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23092680</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Travel Med Infect Dis. 2016 May-Jun;14(3):242-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27189624</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Travel Med Infect Dis. 2018 May - Jun;23:6-13</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29673810</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Microbiol. 2008 Jan;46(1):97-102</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17977985</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2001 Jan 4;344(1):11-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11136954</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Travel Med Infect Dis. 2015 Nov-Dec;13(6):485-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26464001</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect Dis. 2006 Oct 15;194(8):1119-26</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16991087</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Travel Med. 2012 Mar-Apr;19(2):130-2</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22414041</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virulence. 2018;9(1):1354-1363</Citation>
<ArticleIdList><ArticleId IdType="pubmed">30058450</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Infect Control Hosp Epidemiol. 2007 Oct;28(10):1148-54</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17828691</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Travel Med Infect Dis. 2019 Jul - Aug;30:39-45</Citation>
<ArticleIdList><ArticleId IdType="pubmed">31226305</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Arabie saoudite</li>
<li>France</li>
<li>Viêt Nam</li>
</country>
<region><li>Provence-Alpes-Côte d'Azur</li>
</region>
<settlement><li>Marseille</li>
</settlement>
</list>
<tree><country name="France"><region name="Provence-Alpes-Côte d'Azur"><name sortKey="Hoang, Van Thuan" sort="Hoang, Van Thuan" uniqKey="Hoang V" first="Van-Thuan" last="Hoang">Van-Thuan Hoang</name>
</region>
<name sortKey="Belhouchat, Khadidja" sort="Belhouchat, Khadidja" uniqKey="Belhouchat K" first="Khadidja" last="Belhouchat">Khadidja Belhouchat</name>
<name sortKey="Belhouchat, Khadidja" sort="Belhouchat, Khadidja" uniqKey="Belhouchat K" first="Khadidja" last="Belhouchat">Khadidja Belhouchat</name>
<name sortKey="Chaht, Kamel Larbi" sort="Chaht, Kamel Larbi" uniqKey="Chaht K" first="Kamel Larbi" last="Chaht">Kamel Larbi Chaht</name>
<name sortKey="Chaht, Kamel Larbi" sort="Chaht, Kamel Larbi" uniqKey="Chaht K" first="Kamel Larbi" last="Chaht">Kamel Larbi Chaht</name>
<name sortKey="Dao, Thi Loi" sort="Dao, Thi Loi" uniqKey="Dao T" first="Thi-Loi" last="Dao">Thi-Loi Dao</name>
<name sortKey="Dao, Thi Loi" sort="Dao, Thi Loi" uniqKey="Dao T" first="Thi-Loi" last="Dao">Thi-Loi Dao</name>
<name sortKey="De Santi, Vincent Pommier" sort="De Santi, Vincent Pommier" uniqKey="De Santi V" first="Vincent Pommier" last="De Santi">Vincent Pommier De Santi</name>
<name sortKey="De Santi, Vincent Pommier" sort="De Santi, Vincent Pommier" uniqKey="De Santi V" first="Vincent Pommier" last="De Santi">Vincent Pommier De Santi</name>
<name sortKey="De Santi, Vincent Pommier" sort="De Santi, Vincent Pommier" uniqKey="De Santi V" first="Vincent Pommier" last="De Santi">Vincent Pommier De Santi</name>
<name sortKey="Drali, Tassadit" sort="Drali, Tassadit" uniqKey="Drali T" first="Tassadit" last="Drali">Tassadit Drali</name>
<name sortKey="Drali, Tassadit" sort="Drali, Tassadit" uniqKey="Drali T" first="Tassadit" last="Drali">Tassadit Drali</name>
<name sortKey="Fournier, Pierre Edouard" sort="Fournier, Pierre Edouard" uniqKey="Fournier P" first="Pierre-Edouard" last="Fournier">Pierre-Edouard Fournier</name>
<name sortKey="Fournier, Pierre Edouard" sort="Fournier, Pierre Edouard" uniqKey="Fournier P" first="Pierre-Edouard" last="Fournier">Pierre-Edouard Fournier</name>
<name sortKey="Gaudart, Jean" sort="Gaudart, Jean" uniqKey="Gaudart J" first="Jean" last="Gaudart">Jean Gaudart</name>
<name sortKey="Gaudart, Jean" sort="Gaudart, Jean" uniqKey="Gaudart J" first="Jean" last="Gaudart">Jean Gaudart</name>
<name sortKey="Gautret, Philippe" sort="Gautret, Philippe" uniqKey="Gautret P" first="Philippe" last="Gautret">Philippe Gautret</name>
<name sortKey="Gautret, Philippe" sort="Gautret, Philippe" uniqKey="Gautret P" first="Philippe" last="Gautret">Philippe Gautret</name>
<name sortKey="Hoang, Van Thuan" sort="Hoang, Van Thuan" uniqKey="Hoang V" first="Van-Thuan" last="Hoang">Van-Thuan Hoang</name>
<name sortKey="Ly, Tran Duc Anh" sort="Ly, Tran Duc Anh" uniqKey="Ly T" first="Tran Duc Anh" last="Ly">Tran Duc Anh Ly</name>
<name sortKey="Ly, Tran Duc Anh" sort="Ly, Tran Duc Anh" uniqKey="Ly T" first="Tran Duc Anh" last="Ly">Tran Duc Anh Ly</name>
<name sortKey="Mrenda, Bakridine Mmadi" sort="Mrenda, Bakridine Mmadi" uniqKey="Mrenda B" first="Bakridine Mmadi" last="Mrenda">Bakridine Mmadi Mrenda</name>
<name sortKey="Parola, Philippe" sort="Parola, Philippe" uniqKey="Parola P" first="Philippe" last="Parola">Philippe Parola</name>
<name sortKey="Parola, Philippe" sort="Parola, Philippe" uniqKey="Parola P" first="Philippe" last="Parola">Philippe Parola</name>
<name sortKey="Raoult, Didier" sort="Raoult, Didier" uniqKey="Raoult D" first="Didier" last="Raoult">Didier Raoult</name>
<name sortKey="Raoult, Didier" sort="Raoult, Didier" uniqKey="Raoult D" first="Didier" last="Raoult">Didier Raoult</name>
</country>
<country name="Viêt Nam"><noRegion><name sortKey="Hoang, Van Thuan" sort="Hoang, Van Thuan" uniqKey="Hoang V" first="Van-Thuan" last="Hoang">Van-Thuan Hoang</name>
</noRegion>
<name sortKey="Dao, Thi Loi" sort="Dao, Thi Loi" uniqKey="Dao T" first="Thi-Loi" last="Dao">Thi-Loi Dao</name>
</country>
<country name="Arabie saoudite"><noRegion><name sortKey="Yezli, Saber" sort="Yezli, Saber" uniqKey="Yezli S" first="Saber" last="Yezli">Saber Yezli</name>
</noRegion>
<name sortKey="Alotaibi, Badriah" sort="Alotaibi, Badriah" uniqKey="Alotaibi B" first="Badriah" last="Alotaibi">Badriah Alotaibi</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/GrippeFranceV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000017 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000017 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    GrippeFranceV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:31749410
   |texte=   The dynamics and interactions of respiratory pathogen carriage among French pilgrims during the 2018 Hajj.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:31749410" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a GrippeFranceV1

This area was generated with Dilib version V0.6.35.
Data generation: Sun Aug 9 07:31:43 2020. Site generation: Thu Mar 25 22:05:26 2021

	Serveur d'exploration sur la grippe en France
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur la grippe en France

The dynamics and interactions of respiratory pathogen carriage among French pilgrims during the 2018 Hajj.

The dynamics and interactions of respiratory pathogen carriage among French pilgrims during the 2018 Hajj.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki